Tag Archives: pig tissues

Porcine Skin Graft on Human

Xenotransplantation: The Future of Skin Grafts

Xenotransplantation, transplanting animal’s organs into humans, has been studied in research for a long time and is the wave of the future.  Human-to-human organ donation is always in high demand and is very often difficult to procure in a timely fashion to save lives.  Being able to implement animal-to-human transplantation on a routine basis would make saving human lives much easier.  This article speaks of research in porcine skin transplants.  Skin is the largest organ of the body and is critical in the immune system.  Currently skin grafts come from human cadavers and patients that elect to have excess skin removed.  Patients that have been badly burned are always in need of skin grafts.  Porcine skin is incredibly similar to human skin with the exception of the fact that porcine skin produces a sugar that humans do not.  Through genetic modification, this sugar production in the porcine skin has been deleted so it is more conducive to human transplantation. 

This is yet another example of how porcine tissue models help biomedical research. In addition to the live animal models and porcine tissue we provide, we also offer clients expertise in the proper testing, care and housing of live animals.

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The Importance of Porcine Tissues in Research

porcine tissuesThe creatures outside looked from pig to man, and from man to pig, and from pig to man again: but already it was impossible to say which was which.”

That’s George Orwell in Animal Farm, making a political, allegorical, point. But he also could have been talking about biology.

Humans and pigs share a lot of similarities when it comes to anatomy and physiology. Pigs’ organ systems are 80-90 percent similar to those of humans, veterinary researcher Dr. Michael Swindle told FOX News in 2014.

“They are what’s known as a translational research model, so if [something] works in the pig, then it has a high possibility of working in a human,” Swindle said.

That’s why the news last year that researchers had eliminated PERVs – which stands for porcine endogenous retroviruses – in some pig kidney cell DNA was so important.

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