Tag Archives: Pig Models

pigs feeding

The Pig as a Model for the Study of Obesity and of Control of Food Intake

This research study published in the Yale Journal of Biology and Medicine found that people and swine are very similar physiologically in the way that they store fat, and in the size of their fat cells. Scientists are studying the genetics involved in porcine that are lean versus porcine that show much more fat storage. With obesity being a large problem with the human population these days, as well as people’s desire to achieve healthy weights, this research is critical to attaining our collective physical fitness goals. It is fortunate that swine are so similar to people in their fat storage methods.

For more than 30 years, Animal Biotech has helped research teams do this kind of work by providing live porcine models and porcine tissue.  In addition, we also offer clients expertise in the proper testing, care and housing of live animals.

Contact us today to learn how we can assist you in your next project.

Live Animal Model: Pigs in Virus Research

Corona Virus

Research swine are playing an important role in the global fight against COVID-19, with live animal models helping to both create a vaccine and address the worldwide ventilator shortage.

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How Pig Models Help Us Understand Pediatric Nutrition

pig models in pediatric research

Pig models have been instrumental in advances in pediatric nutrition. It’s yet another example of how the biological similarities between research swine and people have helped in human medical research.

A 2017 report by the neuroscience program at the University of Illinois’ Department of Animal Science looked at the scope of this research.

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How Pig Models Are Being Used in Huntington’s Disease Research

swine as models in biomedical researchIn the latest example of the benefits of using swine as models in biomedical research, scientists have engineered the world’s first pigs with Huntington’s disease, which could lead to a cure for this debilitating illness.

Huntington’s is a neurodegenerative disease that leaves its victims incapacitated in its later stages, and in need of personal care.

Symptoms usually present between the ages of 30 and 50 and include trouble concentrating, difficulty swallowing, clumsiness and involuntary jerking. People with the illness rarely survive more than 20 years after their symptoms first manifest.

But there may be hope for people with Huntington’s disease, thanks to a joint effort by researchers at Emory University in Atlanta and Jinan University in China, working with the CRISPR-Cas9 gene editing technique used in swine.

In the past, studies like this one would have used rodents as their main animal model, but these research teams concluded that pigs made a better fit due to their close biological similarity to humans.

“We think the pig model will fill an important gap,” Li Shihua, professor of human genetics at Emory University and one of the study’s co-senior authors, told the Telegraph. “In pigs, the pattern of neurodegeneration is almost the same as in humans, and there have been several treatments tested in mouse models that didn’t translate to humans.”

This study is yet another instance of how using swine as models in biomedical research can lead to breakthroughs that help human patients.

In the past we’ve written about how using swine as models in biomedical research showed new insights into spinal diseases and promising methods for treating diabetes.

Animal Biotech is proud to have played a role in these types of projects. In addition to providing live porcine models and porcine cadavers, we can give your team insights into a host of issues on the testing and housing of live animals.

In addition, we can customize different varieties of post-mortem tissues and tissue blocks or suggest the type of tissue that would work best for your project.

Contact us today to see how Animal Biotech can assist you and your team.