Skin permeation studies are extremely important in predicting percutaneous penetration, and porcine tissue models have proven very important in such research.
A recent study conducted at the University College of London compared skin parallel artificial membrane permeation assay (PAMPA), porcine skin and human skin in the permeation of compounds topically placed on each tissue/artificial tissue.
Continue Reading Studying Skin Permeation with Porcine Tissue Models
If there’s one thread that runs through all our blog posts, it’s the physiological similarity between pigs and humans, a fact that makes the porcine model extremely useful in biomedical research.
For example, there’s the study conducted by researchers at South China Agricultural University and the University of Hawaii at Manoa that looked for the presence of brown adipose tissue (BAT) in pigs.
Continue Reading Determining the Presence of Brown Adipose Tissue in Porcine Models
Wireless capsule endoscopy has been very helpful in making advances in the world of endoscopy, but this work has always been limited to superficial tissue.
However, a there is a new method of pairing ultrasonography with the wireless capsule, allowing doctors to view deeper levels of tissue and therefore have a clearer view of all the tissues involved in the endoscopic procedure.
Continue Reading Porcine Model Used for Wireless Capsule Endoscopy Research
The porcine model has proved to be helpful in establishing the therapeutic effects of mesenchymal stem cells (MSC) in reducing the inflammatory response during acute lung injuries.
In a study conducted at the Tripler Army Medical Center in Honolulu, researchers determined that pigs induced with severe traumatic lung injuries had decreased PVR/SVR levels two hours after treatment with MSCs.
Continue Reading Porcine Model Used for Acute Lung Injury Research
Porcine heart tissue may prove extremely helpful in finding a solution for cardiac failure.
The process of using detergents to decellularize and then recellularize porcine hearts with differentiated cells made from human patient specific pluripotent stem cells is an innovative area of research that may significantly change the prognosis for heart failure patients.
Continue Reading Finding a Solution for Cardiac Failure with Porcine Heart Tissue
Americans spend more than $20 billion dollars a year on wound care, a figure that’s exacerbated by factors such as infections, repeated surgeries and extended hospital stays.
With that in mind, researchers are seeking innovative ways to enhance wound management. One such method is the porcine urinary bladder matrix.
Two recent studies have shown the effectiveness of porcine tissues in treating wounds in both humans and other animals.
Continue Reading Porcine Urinary Bladder Matrix Used to Treat Wounds
Tissues prepared for shipment.
As we discussed last month, abalation is a method used in treating liver tumors. Our previous blog post looked at thermal abalation and porcine liver tissues.
This week, we’ll look at microwave abalation (MWA) in liver tumor treatments and a study by Italian researchers published in 2015 in the Journal of Cancer Surgery.
Continue Reading Microwave Ablation Study Using Porcine Liver
About 75 million Americans have hypertension, a condition that can lead to stroke, heart failure, kidney disease and elevated risk for heart attack.
Treating this condition can be frustrating. Only about half of all people with hypertension have the disease under control.
New research published earlier this year in the journal Cureus looked at the efficacy of treating refractory hypertension through radiosurgical ablation of the renal nerve.
Continue Reading Porcine Models Used to Study Radiosurgical Ablation of the Renal Nerve
Thermal ablation is an important technique in treating liver tumors and metastases. New research into this treatment conducted in Germany relied on porcine liver models to test ablation methods.
This study was conducted by researchers from University Medicine Berlin and Martin Luther University in Halle, and published in April in the Journal of Cellular Biology.
Continue Reading Studying Benign Periablational Enhancement in Porcine Liver Model
Surgeons that perform tendon and ligament replacements are always searching for materials that can mimic the performance and load transmissions of the native material.
As often happens, these searches turn to porcine tissue to approximate human tendons.
In a U.S. patent application filed in 2016, LifeCell Corporation of Branchburg, NJ describes a study using a porcine acellular tissue matrix – derived from porcine skin – that was implanted into a human.
Continue Reading Porcine Tissue Remodeling & Ingrowth