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Category Archives: Post Mortem Tissues

Porcine Tissue Used for Vitreous Cryopreservation Research

PigletVitreous cryopreservation is a practice that allows for the preservation of biomaterials without the risk of excess ice accumulation.

Porcine tissues are an excellent model for this sort of research. There are many stresses – internal, thermal, residual – induced by the rapid cooling process of vitreous cryopreservation.

By using porcine tissues, researchers can fine-tune the methods used in cryopreservation and improve the process, which in turn will allow for effective preservation of larger materials.

Since porcine hepatic tissue is so similar to the liver tissue found in humans, it is an excellent tissue model for vitreous cryopreservation research. A recent study in China – published in the March 2017 edition of the International Journal of Heat and Mass Transfer — used porcine hepatic tissue to look at vitreous cryopreservation.

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Porcine Tissue Teaches Researchers About Human Hearts

porcine tissueIt is important to determine the mechanical behavior of vessels and other soft tissues in order to know how they properly handle loads in all directions (circumferential and longitudinal).

Post-mortem porcine tissue is an excellent model to use in order to test and determine these values.  Researchers are gaining valuable information every day from using porcine tissues which will aid them in being able to repair soft tissues that rupture within humans or animals alike, because they understand how the tissues function under pressure.

A recent study at Aix-Marseille Universite in France – published earlier this month in the Journal of Biomechanics – looked at the mechanical behavior of the porcine ascending aorta as it relates to human ascending aorta pathologies.

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How Porcine Stem Cells Relate to Genome Reprogramming

porcine stem cellsThe limited success of somatic cell nuclear transfer (SCNT) is largely attributed to defects in epigenetic reprogramming of the donor genome.

Donor cell types with distinct potential competence may offer different epigenetic flexibility for subsequent genome reprogramming in SCNT.

To improve the efficiency of cloning, porcine mesenchymal stem cells (pMSCs) were isolated and well identified by 6-channel flow cytometry and differentiation assays and were used as donors in SCNT.  The results suggest that the epigenetic status of donor cells has an improvement on genome reprogramming, and multipotent pMSCs favored subsequent embryonic development.

From Porcine Mesenchymal Stem Cells: Establishment, Differentiation, Electroporation and Nuclear Transfer, by Song, Z., Cong, P., Ji, Q., Chen, L., Nie, Y., Zhao, H., He, Z. and Chen, Y. (2015).  Reproduction in Domestic Animals, 50: 840-848. doi: 10.1111/rda. 12577

At Animal Biotech, we’re proud of our nearly three-decade history of supporting this sort of research by providing the biomedical community with  live high quality research porcine models as well as high quality post mortem tissues, organs, and glands.

Contact us today to find out more about how we can help you with your next project.

Porcine Tissue Can Help Study Marfan Syndrome

porcine tissuePorcine post mortem tissues could be used to augment ATAA (ascending thoracic aortic aneurysm) studies in human normal and Marfan syndrome patients, according to research at the University of Western Ontario’s Department of Medical Biophysics.

In this study the human tissues had to be retrieved from human patients undergoing invasive bypass surgeries as well as from human cadavers. Marfan syndrome is a genetic disorder that affects the body’s connective tissue, and can cause issues with a person’s heart, blood vessels, bones, joints, and eyes.

Because of the anatomical and physiological similarities of porcine to human aortic arteries, post mortem porcine tissue could be substituted experimentally for human tissue thus greatly reducing the time and expense of the research studies.

In the past, porcine tissue has also been used to repair rotator cuffs in human patients, and to regrow muscle tissue.

For over 25 years, Animal Biotech has helped the biomedical community with this sort of research by supplying it with live high quality research porcine models along with high quality post mortem tissues, organs, and glands. We also provide information, consultation and training on most aspects of husbandry, testing, housing and uses of live animals. Contact us today to learn more about how we can assist you in your work.

 

How Domestic Pigs Can Help Cure Human Ailments

porcine tissueThe purpose of animal research is to derive scientific information from animal models that will be used to benefit human health and wellness.

The domestic pig (Sus scrofa) is one of the most valuable animal models used in biomedical research today,  both as a live animal and also as a source of post mortem tissues. This is because of its lower cost, larger size and anatomical, biological and physiological similarity to humans.

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A Focus on Quality Tissue for Research Needs

Highest Standards of Animal Tissue Harvesting

At Animal Biotech Industries (ABI), our mission is to provide clients with high-quality, post-mortem tissues harvested with precise attention to client specifications. All products are harvested at USDA federally inspected abattoirs or at our onsite climate controlled facilities. These harvests are carried out in strictly controlled environmental conditions following precise protocols which have been specifically developed for each client.

Animal Tissue Shipment

These tissue samples are then processed and packaged using time tested techniques that guarantee the integrity of the tissues during shipment. Most tissues are shipped by FedEx either fresh using cold packs or frozen with dry ice. Our packaging and boxing methods allow all tissue to remain in either condition during shipment inside the boxes for up to three days even under the most adverse temperature extremes. We also make it our policy to have contingency plans in place to ensure our clients receive their tissue exactly when they need it, taking into account possible delivery delays with intermediate shipping companies. All FedEx boxes are tracked by both ABI and its clients. Continue Reading A Focus on Quality Tissue for Research Needs