Xenotransplantation, transplanting animal’s organs into humans, has been studied in research for a long time and is the wave of the future. Human-to-human organ donation is always in high demand and is very often difficult to procure in a timely fashion to save lives. Being able to implement animal-to-human transplantation on a routine basis would make saving human lives much easier. This article speaks of research in porcine skin transplants. Skin is the largest organ of the body and is critical in the immune system. Currently skin grafts come from human cadavers and patients that elect to have excess skin removed. Patients that have been badly burned are always in need of skin grafts. Porcine skin is incredibly similar to human skin with the exception of the fact that porcine skin produces a sugar that humans do not. Through genetic modification, this sugar production in the porcine skin has been deleted so it is more conducive to human transplantation.
This is yet another example of how porcine tissue models help biomedical research. In addition to the live animal models and porcine tissue we provide, we also offer clients expertise in the proper testing, care and housing of live animals.
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Can pig islet cells offer a way to combat Parkinson’s disease?
That’s what researchers at Living Cell Technologies in New Zealand hope to learn with the help of research swine.
Over the past few years, this firm has been implanting cells from the choroid plexus of a pig into the brains of Parkinson’s patients to attempt to stop the illness’ progression.
Continue Reading How Pig Cells Could be Used to Slow Parkinson’s Disease
Research swine are contributing to research studies that focus on restorative therapies to replace lost or diseased human tissues.
While the amount of suitable human cells for transplantation is lacking, porcine cells offer researchers a suitable, and much more available, alternative.
In 2014, researchers from the University of Pittsburgh found that cells derived from porcine organs – in this case, bladders – could work with human stem cells help build muscles in the legs of five men who had suffered severe injuries, including two soldiers injured by IEDs.
All five had suffered from nearly 60 percent to 90 percent of leg muscle loss, and had undergone surgery and physical therapy, with no success.
Continue Reading How Porcine Cells Contribute to Restorative Therapies
Skin permeation studies are extremely important in predicting percutaneous penetration, and porcine tissue models have proven very important in such research.
A recent study conducted at the University College of London compared skin parallel artificial membrane permeation assay (PAMPA), porcine skin and human skin in the permeation of compounds topically placed on each tissue/artificial tissue.
Continue Reading Studying Skin Permeation with Porcine Tissue Models