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Category Archives: Porcine Models

How Pig Models Help Us Understand Pediatric Nutrition

pig models in pediatric research

Pig models have been instrumental in advances in pediatric nutrition. It’s yet another example of how the biological similarities between research swine and people have helped in human medical research.

A 2017 report by the neuroscience program at the University of Illinois’ Department of Animal Science looked at the scope of this research.

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How Pig Cells Could be Used to Slow Parkinson’s Disease

Pig islet cells used to slow parkinson's

Can pig islet cells offer a way to combat Parkinson’s disease?

That’s what researchers at Living Cell Technologies in New Zealand hope to learn with the help of research swine.

Over the past few years, this firm has been implanting cells from the choroid plexus of a pig into the brains of Parkinson’s patients to attempt to stop the illness’ progression.

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How Porcine Cells Contribute to Restorative Therapies

porcine cells

Research swine are contributing to research studies that focus on restorative therapies to replace lost or diseased human tissues.

While the amount of suitable human cells for transplantation is lacking, porcine cells offer researchers a suitable, and much more available, alternative.

In 2014, researchers from the University of Pittsburgh found that cells derived from porcine organs – in this case, bladders – could work with human stem cells help build muscles in the legs of five men who had suffered severe injuries, including two soldiers injured by IEDs.

All five had suffered from nearly 60 percent to 90 percent of leg muscle loss, and had undergone surgery and physical therapy, with no success.

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How Porcine Islet Cells Could Help Treat Diabetes

porcine islet cells

Research swine are playing a substantial role in uncovering new methods of treating diabetes.

Porcine islet cells are an integral part of the microislet cell encapsulation method because there is an unlimited source of porcine pancreas cells as compared to human donor pancreatic islets.

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Pig Lumbar Spines Used for Pedicle Screw Testing

Pedicle ScrewsPedicle screws have been the standard method of treatment of spinal diseases.

However, these screws can loosen over time after placement during surgery, which makes them a less-than-ideal choice.

But how can surgeons improve on this practice? The answer may lie within research swine. More specifically, within pig lumbar spines.

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Determining the Presence of Brown Adipose Tissue in Porcine Models

adipose cell on microscopeIf there’s one thread that runs through all our blog posts, it’s the physiological similarity between pigs and humans, a fact that makes the porcine model extremely useful in biomedical research.

For example, there’s the study conducted by researchers at South China Agricultural University and the University of Hawaii at Manoa that looked for the presence of brown adipose tissue (BAT) in pigs.

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Porcine Model Used for Wireless Capsule Endoscopy Research

Endoscopy Capsule Research using Porcine TissueWireless capsule endoscopy has been very helpful in making advances in the world of endoscopy, but this work has always been limited to superficial tissue.

However, a there is a new method of pairing ultrasonography with the wireless capsule, allowing doctors to view deeper levels of tissue and therefore have a clearer view of all the tissues involved in the endoscopic procedure.

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Porcine Model Used for Acute Lung Injury Research

porcine model for lung researchThe porcine model has proved to be helpful in establishing the therapeutic effects of mesenchymal stem cells (MSC) in reducing the inflammatory response during acute lung injuries.

In a study conducted at the Tripler Army Medical Center in Honolulu, researchers determined that pigs induced with severe traumatic lung injuries had decreased PVR/SVR levels two hours after treatment with MSCs.

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Porcine Models Used to Study Radiosurgical Ablation of the Renal Nerve

porcine cadaverAbout 75 million Americans have hypertension, a condition that can lead to stroke, heart failure, kidney disease and elevated risk for heart attack.

Treating this condition can be frustrating. Only about half of all people with hypertension have the disease under control.

New research published earlier this year in the journal Cureus looked at the efficacy of treating refractory hypertension through radiosurgical ablation of the renal nerve.

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