Category Archives: Porcine Models

simple rendering of human lungs in shades of blue

Porcine Organ Block as a Thoracoscopic Lobectomy Model

In medical disciplines such as surgery, it is crucial for practitioners to have hands-on experience with procedures before performing them in a clinical setting.  This is easier said than done: certain operations are difficult to replicate outside of a living subject.  It can also be difficult to access and learn on practice models outside of an educational setting, posing a problem for practicing surgeons who want to utilize techniques developed after the completion of their education.  Animal models and tissues provide one solution to this problem, allowing students and professionals to develop their skills on non-human subjects.  This article from The Annals of Thoracic Surgery describes one such simulator for the practice of thoracoscopic lobectomy.

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Male doctor in surgical clothes looking at vertebral mri scan headshot

Swine Brain Development as a Research Model for Human Neurology

Humans and swine are known to have great similarities when it comes to anatomy and physiology, making swine an excellent model for research. This article is very interesting because it shows that early swine brain development is very similar to that of humans. It is intriguing to see how these animals compare to children (both at early ages and weights) in their MRI imaging. It is always great to be able to have the research be directly applicable to humans, because the diagnostic tool is one that is being used with people currently. Humans have MRIs done easily and it is something that can easily be instituted to help diagnose children with neurologic disorders. This study focused on body weight rather than age when it came to matching the children to the pigs, and it was found that this method of matching between animal and human worked out very well. There was a little bit of variation in certain chemical levels (CBF) that were being measured but that may also be linked to the anesthesia drugs that were used to anesthetize the animals. This research is very promising and will certainly help future children.

At Animal Biotech, we take great pride in the part that we’ve played in this sort of research. We not only provide live research swine and porcine tissue: we’re also here to offer our expertise on the proper care and housing of live animals.

Contact us today to learn how we can assist you in your next project.

pigs feeding

The Pig as a Model for the Study of Obesity and of Control of Food Intake

This research study published in the Yale Journal of Biology and Medicine found that people and swine are very similar physiologically in the way that they store fat, and in the size of their fat cells. Scientists are studying the genetics involved in porcine that are lean versus porcine that show much more fat storage. With obesity being a large problem with the human population these days, as well as people’s desire to achieve healthy weights, this research is critical to attaining our collective physical fitness goals. It is fortunate that swine are so similar to people in their fat storage methods.

For more than 30 years, Animal Biotech has helped research teams do this kind of work by providing live porcine models and porcine tissue.  In addition, we also offer clients expertise in the proper testing, care and housing of live animals.

Contact us today to learn how we can assist you in your next project.

Man's hand holding a stent between forefinger and thumb in front of his eye. Selective focus on the stent.

Thrombectomy Study in Pigs

Stents have long been a part of the lives of people. It is critical to keep clots and emboli in check to maintain the vascular health of people. Stent retriever mechanical thrombectomy is used standardly in treatment of strokes. The research done in this article on thrombectomy in acute stroke treatment is groundbreaking. The NeVa thrombectomy device is showing that it is able to collect and therefore remove large clot occlusions from the vascular system and achieve near-full to full reperfusion. The design of the device lends itself very well to capturing these clots. Swine are the model of choice for this study because their vascular system so closely matches the human vascular system.

We’re proud of the work our animals help researchers accomplish and look forward to contributing research swine to help in similar breakthroughs in the future.

In addition to offering live porcine models and porcine tissue, we’re also happy to offer clients our expertise in selecting the right animal model and/or animal tissue to utilize in their research.

Contact us today to learn how we can help you make your next discovery with the help of our high-quality animal models and tissues.

Anterior Cruciate Ligament in x-ray view

Comparison of Domestic Pig and Human Cruciate Ligaments

This research published in the Journal of Anatomy was done to compare human and porcine cruciate ligaments (namely the ACL and PCL) in their form and function.  The similarity of these two ligaments between people and swine are amazing.  It was noted, however, that the pig and the person differ in their gaits and it is difficult to fully match their movements and tensions on the ligaments.  Still, researchers are finding that people and swine are similar enough to be able to compare them on many other levels and their findings will benefit people with ligament injuries with further research.

Animal Biotech is pleased to play a role in this sort of research, offering live research swine and porcine tissue – along with expertise on proper animal care – to the biomedical world. Contact us today to learn how we can assist you with your next project.

Live Animal Model: Pigs in Virus Research

Corona Virus

Research swine are playing an important role in the global fight against COVID-19, with live animal models helping to both create a vaccine and address the worldwide ventilator shortage.

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Four Ways Porcine Models May Improve Human Health

group of pigs outside, raised to be porcine models

Regular readers of our blog have probably picked up on a pattern: story after story about how porcine models have helped lead to breakthroughs that can improve human health.

From Parkinson’s disease to diabetes to pediatric nutrition, there are numerous examples of this phenomenon. Here are a few that we’ve noted recently.

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How Pig Models Help Us Understand Pediatric Nutrition

doctor with juvenile patient, discussing pediatric nutrition

Pig models have been instrumental in advances in pediatric nutrition. It’s yet another example of how the biological similarities between research swine and people have helped in human medical research.

A 2017 report by the neuroscience program at the University of Illinois’ Department of Animal Science looked at the scope of this research.

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How Pig Cells Could be Used to Slow Parkinson’s Disease

close-up of hands of man with Parkinson’s Disease

Can pig islet cells offer a way to combat Parkinson’s disease?

That’s what researchers at Living Cell Technologies in New Zealand hope to learn with the help of research swine.

Over the past few years, this firm has been implanting cells from the choroid plexus of a pig into the brains of Parkinson’s patients to attempt to stop the illness’ progression.

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