Xenotransplantation, transplanting animal’s organs into humans, has been studied in research for a long time and is the wave of the future. Human-to-human organ donation is always in high demand and is very often difficult to procure in a timely fashion to save lives. Being able to implement animal-to-human transplantation on a routine basis would make saving human lives much easier. This article speaks of research in porcine skin transplants. Skin is the largest organ of the body and is critical in the immune system. Currently skin grafts come from human cadavers and patients that elect to have excess skin removed. Patients that have been badly burned are always in need of skin grafts. Porcine skin is incredibly similar to human skin with the exception of the fact that porcine skin produces a sugar that humans do not. Through genetic modification, this sugar production in the porcine skin has been deleted so it is more conducive to human transplantation.
This is yet another example of how porcine tissue models help biomedical research. In addition to the live animal models and porcine tissue we provide, we also offer clients expertise in the proper testing, care and housing of live animals.
Contact us today to learn how we can help you with your next project.
Research swine are playing an important role in the global fight against COVID-19, with live animal models helping to both create a vaccine and address the worldwide ventilator shortage.
Continue Reading Live Animal Model: Pigs in Virus Research
Researchers in China have genetically engineered a pig with human DNA and transplanted skin grafts onto monkeys, a breakthrough they say will open the door to new skin/organ transplants.
Continue Reading Research Pigs Lead to Milestone in Skin Transplants
Medical researchers have long recognized the efficacy of using live pig models to understand illnesses in humans better.
But a new study out of the University of Georgia suggests that pig brains are even more effective for neurological research than once thought.
Using an imaging method typically reserved for humans, the research team at the university’s Regenerative Bioscience Center found that pig brains can offer new insights into neurological conditions such as Parkinson’s and Alzheimer’s diseases.
Continue Reading How Pig Models Help Us Understand the Human Brain
Regular readers of our blog have probably picked up on a pattern: story after story about how porcine models have helped lead to breakthroughs that can improve human health.
From Parkinson’s disease to diabetes to pediatric nutrition, there are numerous examples of this phenomenon. Here are a few that we’ve noted recently.
Continue Reading Four Ways Porcine Models May Improve Human Health
Super-dosing of phytase in young pigs has been shown to improve their iron levels, according to a study conducted by AB Vista.
Newborn piglets typically receive injected iron supplements, as they are born with low stores of iron and their mothers’ milk is not able to provide the needed iron requirements.
Continue Reading Phytase Super-dosing Improves Iron levels in Pigs & Humans
Researchers at Yale University have used an artificial blood replacement to restore activity to porcine brains hours after their death.
Continue Reading Dead Pig Brains Show Life
For people with end-stage heart failure, getting a heart transplant can be the difference between life and death when all other treatments have failed.
Yet finding a suitable donor can often be difficult, which is why the medical community has turned to xenotransplantation – organ transplants from one species to another – for a solution.
Continue Reading Pig Organs Offer New Hopes for Heart Transplants
They were men who had suffered unimaginable injuries.
Two of them were ex-soldiers, wounded by explosives. They had lost anywhere from 60 to 90 percent of the muscles in their legs.
Things seemed hopeless even after surgery and physical therapy. Then came an experimental study, involving pig bladders from research swine.
Continue Reading Scientists Regenerate Leg Muscles Using Pig Bladder Tissue
Pig models have been instrumental in advances in pediatric nutrition. It’s yet another example of how the biological similarities between research swine and people have helped in human medical research.
A 2017 report by the neuroscience program at the University of Illinois’ Department of Animal Science looked at the scope of this research.
Continue Reading How Pig Models Help Us Understand Pediatric Nutrition