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Pig Lumbar Spines Used for Pedicle Screw Testing

Pedicle ScrewsPedicle screws have been the standard method of treatment of spinal diseases.

However, these screws can loosen over time after placement during surgery, which makes them a less-than-ideal choice.

But how can surgeons improve on this practice? The answer may lie within research swine. More specifically, within pig lumbar spines.

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Studying Skin Permeation with Porcine Tissue Models

Porcine SkinSkin permeation studies are extremely important in predicting percutaneous penetration, and porcine tissue models have proven very important in such research.

A recent study conducted at the University College of London compared skin parallel artificial membrane permeation assay (PAMPA), porcine skin and human skin in the permeation of compounds topically placed on each tissue/artificial tissue.

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Determining the Presence of Brown Adipose Tissue in Porcine Models

adipose cell on microscopeIf there’s one thread that runs through all our blog posts, it’s the physiological similarity between pigs and humans, a fact that makes the porcine model extremely useful in biomedical research.

For example, there’s the study conducted by researchers at South China Agricultural University and the University of Hawaii at Manoa that looked for the presence of brown adipose tissue (BAT) in pigs.

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Porcine Model Used for Wireless Capsule Endoscopy Research

Endoscopy Capsule Research using Porcine TissueWireless capsule endoscopy has been very helpful in making advances in the world of endoscopy, but this work has always been limited to superficial tissue.

However, a there is a new method of pairing ultrasonography with the wireless capsule, allowing doctors to view deeper levels of tissue and therefore have a clearer view of all the tissues involved in the endoscopic procedure.

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Porcine Model Used for Acute Lung Injury Research

porcine model for lung researchThe porcine model has proved to be helpful in establishing the therapeutic effects of mesenchymal stem cells (MSC) in reducing the inflammatory response during acute lung injuries.

In a study conducted at the Tripler Army Medical Center in Honolulu, researchers determined that pigs induced with severe traumatic lung injuries had decreased PVR/SVR levels two hours after treatment with MSCs.

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Finding a Solution for Cardiac Failure with Porcine Heart Tissue

Porcine Tissue for Cardiac FailurePorcine heart tissue may prove extremely helpful in finding a solution for cardiac failure.

The process of using detergents to decellularize and then recellularize porcine hearts with differentiated cells made from human patient specific pluripotent stem cells is an innovative area of research that may significantly change the prognosis for heart failure patients.

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Porcine Urinary Bladder Matrix Used to Treat Wounds

HAmericans spend more than $20 billion dollars a year on wound care, a figure that’s exacerbated by factors such as infections, repeated surgeries and extended hospital stays.

With that in mind, researchers are seeking innovative ways to enhance wound management. One such method is the porcine urinary bladder matrix.

Two recent studies have shown the effectiveness of porcine tissues in treating wounds in both humans and other animals.

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Microwave Ablation Study Using Porcine Liver

tissue shipment

Tissues prepared for shipment.

As we discussed last month, abalation is a method used in treating liver tumors. Our previous blog post looked at thermal abalation and porcine liver tissues.

This week, we’ll look at microwave abalation (MWA) in liver tumor treatments and a study by Italian researchers published in 2015 in the Journal of Cancer Surgery.

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Porcine Models Used to Study Radiosurgical Ablation of the Renal Nerve

porcine cadaverAbout 75 million Americans have hypertension, a condition that can lead to stroke, heart failure, kidney disease and elevated risk for heart attack.

Treating this condition can be frustrating. Only about half of all people with hypertension have the disease under control.

New research published earlier this year in the journal Cureus looked at the efficacy of treating refractory hypertension through radiosurgical ablation of the renal nerve.

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Studying Benign Periablational Enhancement in Porcine Liver Model

iStock_000003693823_SmallThermal ablation is an important technique in treating liver tumors and metastases. New research into this treatment conducted in Germany relied on porcine liver models to test ablation methods.

This study was conducted by researchers from University Medicine Berlin and Martin Luther University in Halle, and published in April in the Journal of Cellular Biology.

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