About 75 million Americans have hypertension, a condition that can lead to stroke, heart failure, kidney disease and elevated risk for heart attack.
Treating this condition can be frustrating. Only about half of all people with hypertension have the disease under control.
New research published earlier this year in the journal Cureus looked at the efficacy of treating refractory hypertension through radiosurgical ablation of the renal nerve.
Continue Reading Porcine Models Used to Study Radiosurgical Ablation of the Renal Nerve
Thermal ablation is an important technique in treating liver tumors and metastases. New research into this treatment conducted in Germany relied on porcine liver models to test ablation methods.
This study was conducted by researchers from University Medicine Berlin and Martin Luther University in Halle, and published in April in the Journal of Cellular Biology.
Continue Reading Studying Benign Periablational Enhancement in Porcine Liver Model
Surgeons that perform tendon and ligament replacements are always searching for materials that can mimic the performance and load transmissions of the native material.
As often happens, these searches turn to porcine tissue to approximate human tendons.
In a U.S. patent application filed in 2016, LifeCell Corporation of Branchburg, NJ describes a study using a porcine acellular tissue matrix – derived from porcine skin – that was implanted into a human.
Continue Reading Porcine Tissue Remodeling & Ingrowth
An abdominal wall hernia is a weakness in the muscles of your abdominal wall that can cause pain and bulging of the fat or intestines.
The abdominal wall is comprised of muscles and connective tissue. A hernia occurs when there is a tear in the wall, allowing what is behind the wall to push through.
Continue Reading Porcine Models Used for Abdominal Wall Hernia Repair
The cells that make up our bodies are surrounded by an extracellular matrix – ECM – which provides support for the cells.
When there is damage to the cells, tissue must be regenerated. This regeneration depends on a series of physiological events.
The first stage of this process is the inflammatory phase. After many other cells migrate to the damaged site, the differentiated cells produce and deposit new extracellular matrix.
Studies, such as the one published last year by LifeCell Corporation in New Jersey, have used porcine dermal tissue to make a biocompatible mesh to repair multiple damaged tissues, while minimizing infections or adhesions.
Continue Reading Biocompatible Mesh Graft from Porcine Dermal Tissue
Porcine renal tissue is useful in studying ultrasound elastography, a method of measuring the graft health of a transplanted kidney.
A recent study by researchers at the University of British Columbia found that blood pressure plays a role as a confounding factor in measuring the elasticity of the renal tissue.
Continue Reading A Study of Ultrasound Elastography Using Porcine Renal Tissue
As we’ve pointed out multiple times on this blog, porcine tissue is used in research because of pigs’ biological similarities to humans.
That was the case yet again in a study conducted by researchers from the Departments of Chemical Engineering and Biological Sciences at Rowan University and the Department of Biomedical Engineering at Drexel University.
Continue Reading Studying Injectable Biomaterials on Porcine Tissue
Vitreous cryopreservation is a practice that allows for the preservation of biomaterials without the risk of excess ice accumulation.
Porcine tissues are an excellent model for this sort of research. There are many stresses – internal, thermal, residual – induced by the rapid cooling process of vitreous cryopreservation.
By using porcine tissues, researchers can fine-tune the methods used in cryopreservation and improve the process, which in turn will allow for effective preservation of larger materials.
Since porcine hepatic tissue is so similar to the liver tissue found in humans, it is an excellent tissue model for vitreous cryopreservation research. A recent study in China – published in the March 2017 edition of the International Journal of Heat and Mass Transfer — used porcine hepatic tissue to look at vitreous cryopreservation.
Continue Reading Porcine Tissue Used for Vitreous Cryopreservation Research
As we’ve pointed out in previous blog posts, porcine models are helpful in the study of human wound healing, because pigs and humans have very similar skin.
Porcine models played a role in a recent study at the University of Reading in Great Britain that looked at the use of cryogels and hydrogels in wound care applications.
Hydrogels are well known for their ability to aid in wound healing by accelerating the healing process such as reducing the amount of dehydration in the wound bed and absorbing exudate.
Continue Reading Cryogels for Wound Care Applications in Porcine Models
Pigs regularly play an important role in vital medical research through the use of porcine organs and tissues.
One such area is the field known as TERM, or tissue engineering and regenerative medicine. Tissue regeneration can change the lives of humans and animals alike, making progress in this field of research even more critical.
Continue Reading Porcine Organs Used in Tissue Engineering and Regenerative Medicine